Group of Dr. Traube - Faculty for Chemistry and Pharmacy

Publications

2022

Aumer T*, Gremmelmaier CB*, Runtsch LS*, Pforr JC, Yeşiltaç GN, Kaiser S, Traube FR# “Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line” Clin. Epigenetics 14 (2022), 113.

Traube FR*, Stern M*, Tölke AJ*, Rudelius M, Mejías-Pérez E, Raddaoui N, Kümmerer BM, Douat C, Streshnev F, Albanese M, Wratil PR, Gärtner YV, Nainyte M, Giorgio G, Michalakis S, Schneider S, Streeck H, Müller M, Keppler OT#, Carell T#. "Suppression of SARS-CoV-2 Replication with Stabilized and Click-Chemistry Modified siRNAs" Angew. Chem. Ed. Int. Engl. (2022), accepted article

Traube FR#, Brás NF, Roos WP, Sommermann CC, Diehl T, Mayer RJ, Ofial AR, Müller M, Zipse H, Carell T# “Epigenetic anti-cancer treatment with a stabilized carbocyclic Decitabine analogue“ Chem. Eur. J. 28 (2022), e202200640.

Panosyan H#, Traube FR, Brandmayr C, Wagner M, Carell T#. “tRNA modification profiles in obligate and moderate thermophilic bacilli” Extremophiles 26 (2022), 11.


2021

Traube FR, Özdemir D, Sahin H, Scheel C, Glück AF, Geserich AS, Oganesian S, Kostidis S, Iwan K, Rahimoff R, Giorgio G, Müller M, Spada F, Biel M, Cox J, Giera M, Michalakis S#, Carell T#. “Redirected nuclear glutamate dehydrogenase supplies Tet3 with a-ketoglutarate in neurons“ Nat. Commun. 12 (2021), 4100.

Schelter F, Kirchner A, Traube FR, Müller M, Steglich W, Carell T#. “5-Hydroxymethyl-, 5-Formyl- and 5-Carboxydeoxycytidines as Oxidative Lesions and Epigenetic Marks” Chem. Eur. J. 27 (2021), 8100 – 8104.

Traube FR*, Schiffers S*, Carell T#. “Quantification of DNA Methylation and Its Oxidized Derivatives Using LC-MS” Methods Mol. Biol. 2272 (2021), 77 – 94.


2020

Koch M, Scheel C, Ma H, Yang F, Stadlmeier M, Glück AF, Murenu E, Traube FR, Carell T, Biel M, Ding XQ, Michalakis S#. “The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia” Int. J. Mol. Sci. 22 (2020), E52.

Mulholland CB, Nishiyama A, Ryan J, Nakamura R, Yiğit M, Glück IM, Trummer C, Qin W, Bartoschek MD, Traube FR, Parsa E, Ugur E, Modic M, Acharya A, Stolz P, Ziegenhain C, Wierer M, Enard W, Carell T, Lamb DC, Takeda H, Nakanishi M, Bultmann S#, Leonhardt H# “Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals” Nat. Commun. 11 (2020), 5972.

Mulholland CB, Traube FR, Ugur E, Parsa E, Eckl EM, Schönung M, Modic M, Bartoschek MD, Stolz P, Ryan J, Carell T, Leonhardt H#, Bultmann S#. “Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency” Sci. Rep. 10 (2020), 12066.


2019

Wildenhof TM, Schiffers S, Traube FR, Mayer P, Carell T#. “Influencing Epigenetic Information with a Hydrolytically Stable Carbocyclic 5-Aza-2’-deoxycytidine” Angew. Chem. Int. Ed. Engl. 58 (2019), 12984 – 12987.

Traube FR*, Schiffers S*, Iwan K*, Kellner S, Spada F, Müller M, Carell T#. “Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides” Nat. Protoc. 14 (2019), 283 – 312.


2017

Traube FR#, Carell T#. “The chemistries and consequences of DNA and RNA methylation and demethylation” RNA Biol. 14 (2017), 1099 – 1107.


2016

Schröder AS*, Parsa E*, Iwan K, Traube FR, Wallner M, Serdjukow S, Carell T#. “2‘-(R)-Fluorinated mC, hmC, fC and caC triphosphates are substrates for DNA polymerases and TET-enzymes” Chem. Commun. 52 (2016), 14361 – 14364.


* Shared first authors; # corresponding author(s)